Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | EEF2K | O00418 | 2/20 | 0.45 |
| ▸ | TACR1 | P25103 | 2/20 | 0.43 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.43 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.43 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.43 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.43 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.42 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.42 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.42 |
| ▸ | LDHA | P00338 | 1/20 | 0.41 |
| ▸ | LDHB | P07195 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | FNTA | P49354 | 1/20 | 0.41 |
| ▸ | FNTB | P49356 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8303021 | 0.89 | ALDH1A1 (0.47) | TACR1MEN1POLBKMT2AALDH1A1 | |
| SCHEMBL8306927 | 0.85 | EPHX1 (0.50) | CNR2MEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL7994713 | 0.78 | MEN1 (0.58) | CNR2EEF2KLDHALDHBMEN1 | |
| SCHEMBL8306436 | 0.76 | ALDH1A1 (0.47) | MEN1KMT2ACYP1A2CYP2D6ALDH1A1 | |
| SCHEMBL8305705 | 0.75 | EPHX1 (0.45) | CNR2CYP1A2CYP2C19CYP2D6ALDH1A1 | |
| SCHEMBL5364020 | 0.75 | THRB (0.45) | CNR2EEF2KLDHALDHBMEN1 | |
| SCHEMBL5312465 | 0.74 | MEN1 (0.51) | MEN1POLBKMT2ACYP3A4ALDH1A1 | |
| SCHEMBL24036553 | 0.74 | THRB (0.47) | CNR2EEF2KLDHALDHBMEN1 | |
| SCHEMBL3738074 | 0.74 | UTS2R (0.43) | CNR2TACR1MEN1KMT2ACYP1A2 | |
| SCHEMBL3738078 | 0.74 | UTS2R (0.43) | CNR2TACR1MEN1KMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004085661-A2 | PROCESS TO CHIRAL BETA-AMINO ACID DERIVATIVES | MERCK & CO., INC (US) | 2004-10-07 | — | — | WO | disclosed |