SCHEMBL8305575

SCHEMBL8305575

C=C(C)/C=C\C(=C/C)N1CCOC1=O

nearest known ligand 0.41

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 12/20 0.40
FAAH O00519 3/20 0.32
NOTUM Q6P988 1/20 0.31
PIK3CD O00329 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8311338 0.78 NAAA (0.41) NAAAFAAH
SCHEMBL3130166 0.74
SCHEMBL8306796 0.73 FAAH (0.40) NAAAFAAH
SCHEMBL13705840 0.72 LMNA (0.40)
SCHEMBL13705820 0.71 LMNA (0.39)
SCHEMBL13705848 0.71 KLK5 (0.32) NAAAFAAH
SCHEMBL13716797 0.70
SCHEMBL631172 0.69 NAAA (0.45) NAAAFAAHNOTUMPIK3CD
SCHEMBL8343025 0.69 NAAA (0.33) NAAAPIK3CD
SCHEMBL4806247 0.68 NAAA (0.44) NAAAFAAHNOTUMPIK3CD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017201187-A1 LIM KINASE INHIBITORS VIRONGY, LLC (US) 2017-11-23 WO disclosed
WO-2004082687-A1 LACTAM-CONTAINING CYCLIC DIAMINES AND DERIVATIVES AS FACTOR XA INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 2004-09-30 WO disclosed