Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | NAAA | Q02083 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13705848 | 0.90 | KLK5 (0.32) | FAAHNAAANPSR1MAPT | |
| SCHEMBL13716797 | 0.80 | — | — | |
| SCHEMBL8305577 | 0.78 | FAAH (0.41) | FAAHNAAANPSR1ALDH1A1POLB | |
| SCHEMBL8305575 | 0.73 | NAAA (0.40) | FAAHNAAA | |
| SCHEMBL13705840 | 0.72 | LMNA (0.40) | ALDH1A1HSD17B10MAPT | |
| SCHEMBL13705820 | 0.71 | LMNA (0.39) | ALDH1A1HSD17B10MAPT | |
| SCHEMBL4184664 | 0.69 | NPSR1 (0.47) | FAAHNAAANPSR1ALDH1A1POLB | |
| SCHEMBL13705824 | 0.69 | FAAH (0.33) | FAAHNAAA | |
| SCHEMBL22174819 | 0.68 | CA2 (0.32) | — | |
| SCHEMBL13717113 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004082687-A1 | LACTAM-CONTAINING CYCLIC DIAMINES AND DERIVATIVES AS FACTOR XA INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2004-09-30 | — | — | WO | disclosed |