Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13705824 | 0.91 | FAAH (0.33) | FAAHNAAA | |
| SCHEMBL20037922 | 0.81 | — | — | |
| SCHEMBL20038190 | 0.79 | ATM (0.30) | — | |
| SCHEMBL8306796 | 0.78 | FAAH (0.40) | FAAHNAAANPSR1ALDH1A1POLB | |
| SCHEMBL8311338 | 0.75 | NAAA (0.41) | FAAHNAAA | |
| SCHEMBL13705841 | 0.74 | LMNA (0.38) | ALDH1A1HSD17B10MAPT | |
| SCHEMBL8343025 | 0.73 | NAAA (0.33) | NAAA | |
| SCHEMBL13705816 | 0.73 | LMNA (0.37) | ALDH1A1HSD17B10MAPT | |
| SCHEMBL8312444 | 0.72 | — | — | |
| SCHEMBL27841200 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004082687-A1 | LACTAM-CONTAINING CYCLIC DIAMINES AND DERIVATIVES AS FACTOR XA INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2004-09-30 | — | — | WO | disclosed |