Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL8306061 | 0.83 | L3MBTL1 (0.34) | HPGDL3MBTL1ATMNPC1RAB9A | |
| SCHEMBL8305735 | 0.78 | CYP1A2 (0.34) | HPGDL3MBTL1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8301307 | 0.76 | HSD17B10 (0.39) | HPGDNPC1RAB9ASMN1; SMN2CYP1A2 | |
| SCHEMBL8304121 | 0.72 | ALDH1A1 (0.41) | L3MBTL1SMN1; SMN2ALDH1A1MAPTTP53 | |
| SCHEMBL8434188 | 0.69 | L3MBTL1 (0.38) | HPGDL3MBTL1ATMALDH1A1KDM4E | |
| SCHEMBL8326659 | 0.64 | KDM4E (0.45) | HPGDCYP1A2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL11037027 | 0.63 | ALDH1A1 (0.42) | HPGDL3MBTL1ATMNPC1SMN1; SMN2 | |
| Acetic Acid SCHEMBL8306059 | 0.62 | L3MBTL1 (0.32) | HPGDL3MBTL1ATMNPC1RAB9A | |
| SCHEMBL27492109 | 0.60 | GAA (0.54) | L3MBTL1ALDH1A1MAPTTP53CHRM2 | |
| SCHEMBL8300493 | 0.60 | ALDH1A1 (0.39) | SMN1; SMN2ALDH1A1MAPTKMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0944621-A1 | 2-IMIDAZOLINYLAMINOINDOLE COMPOUNDS USEFUL AS ALPHA-2 ADRENOCEPTOR AGONISTS | THE PROCTER & GAMBLE COMPANY (US) | 1999-09-29 | — | — | EP | disclosed |
| WO-1998023610-A1 | 2-IMIDAZOLINYLAMINOINDOLE COMPOUNDS USEFUL AS ALPHA-2 ADRENOCEPTOR AGONISTS | THE PROCTER & GAMBLE COMPANY (US) | 1998-06-04 | — | — | WO | disclosed |