Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL8306059 | 0.81 | L3MBTL1 (0.32) | MAPK1KDM4ESMN1; SMN2NPC1HPGD | |
| SCHEMBL8301307 | 0.79 | HSD17B10 (0.39) | CYP1A2CYP2C9CYP2C19HSD17B10MAPK1 | |
| SCHEMBL8305736 | 0.78 | HPGD (0.34) | CYP1A2CYP2C9CYP2C19HSD17B10MAPK1 | |
| SCHEMBL8304121 | 0.76 | ALDH1A1 (0.41) | HSD17B10MAPK1KDM4ESMN1; SMN2LMNA | |
| SCHEMBL8438884 | 0.73 | SMN1; SMN2 (0.34) | CYP1A2CYP2C9CYP2C19KDM4ESMN1; SMN2 | |
| SCHEMBL8434188 | 0.72 | L3MBTL1 (0.38) | MAPK1KDM4EHPGDLMNAALDH1A1 | |
| SCHEMBL8326659 | 0.67 | KDM4E (0.45) | CYP1A2CYP2C9CYP2C19HSD17B10KDM4E | |
| SCHEMBL11037027 | 0.66 | ALDH1A1 (0.42) | CYP1A2CYP2C19MAPK1CYP2D6SMN1; SMN2 | |
| SCHEMBL9033856 | 0.65 | RAB9A (0.38) | CYP1A2CYP2C9CYP2C19MAPK1KDM4E | |
| SCHEMBL30404697 | 0.64 | ALDH1A1 (0.40) | NPC1HPGDRAB9ALMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0944621-A1 | 2-IMIDAZOLINYLAMINOINDOLE COMPOUNDS USEFUL AS ALPHA-2 ADRENOCEPTOR AGONISTS | THE PROCTER & GAMBLE COMPANY (US) | 1999-09-29 | — | — | EP | disclosed |
| WO-1998023610-A1 | 2-IMIDAZOLINYLAMINOINDOLE COMPOUNDS USEFUL AS ALPHA-2 ADRENOCEPTOR AGONISTS | THE PROCTER & GAMBLE COMPANY (US) | 1998-06-04 | — | — | WO | disclosed |