Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | GLA | P06280 | 1/20 | 0.57 |
| ▸ | CASP6 | P55212 | 1/20 | 0.54 |
| ▸ | HCAR3 | P49019 | 3/20 | 0.50 |
| ▸ | CDC25B | P30305 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.44 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.44 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8300884 | 0.84 | CASP6 (0.49) | KDM4EGLACASP6HCAR3POLB | |
| SCHEMBL8442696 | 0.84 | ALDH1A1 (0.48) | KDM4EGLACASP6HCAR3ALDH1A1 | |
| SCHEMBL8305961 | 0.83 | ALDH1A1 (0.50) | KDM4EGLACASP6HCAR3ATM | |
| SCHEMBL8303776 | 0.82 | ATM (0.65) | KDM4EGLACASP6HCAR3ATM | |
| SCHEMBL8304450 | 0.82 | CASP6 (0.47) | KDM4EGLACASP6HCAR3POLB | |
| SCHEMBL1805157 | 0.77 | KDM4E (0.51) | KDM4EGLAPOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL7408912 | 0.76 | TSHR (0.56) | KDM4EPOLBATMALDH1A1SMN1; SMN2 | |
| SCHEMBL7374190 | 0.76 | ALDH1A1 (0.48) | KDM4EGLAALDH1A1SMN1; SMN2AKR1C3 | |
| SCHEMBL7371553 | 0.75 | ALDH1A1 (0.46) | ATMALDH1A1SMN1; SMN2TSHRMEN1 | |
| SCHEMBL7371278 | 0.74 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2TSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934068-A1 | COMPOUNDS AND METHODS | SMITHKLINE BEECHAM CORPORATION (US) | 1999-08-11 | — | — | EP | disclosed |
| WO-1998009630-A1 | COMPOUNDS AND METHODS | SMITHKLINE BEECHAM CORPORATION (US) | 1998-03-12 | — | — | WO | disclosed |