Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.55 |
| ▸ | HTR1A | P08908 | 3/20 | 0.55 |
| ▸ | ACHE | P22303 | 4/20 | 0.51 |
| ▸ | BCHE | P06276 | 3/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.51 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9073679 | 0.99 | HTR2A (0.54) | HTR2AHTR1AACHEBCHESLC6A4 | |
| SCHEMBL8306860 | 0.95 | HTR1A (0.62) | HTR1AACHEBCHESLC6A4DRD2 | |
| SCHEMBL8310233 | 0.85 | HTR1A (0.60) | HTR2AHTR1AACHESLC6A4DRD2 | |
| SCHEMBL8307225 | 0.83 | NQO2 (0.47) | HTR2AHTR1ASLC6A4DRD2 | |
| Hydrochloric Acid SCHEMBL8913070 | 0.83 | NQO2 (0.46) | HTR2AHTR1ASLC6A4DRD2 | |
| SCHEMBL11739332 | 0.80 | HTR2A (0.69) | HTR2AHTR1ASLC6A4DRD2 | |
| SCHEMBL8310519 | 0.79 | NQO2 (0.46) | HTR2AHTR1ASLC6A4DRD2 | |
| Hydrochloric Acid SCHEMBL8912255 | 0.78 | NQO2 (0.45) | HTR2AHTR1ASLC6A4DRD2 | |
| SCHEMBL31579316 | 0.77 | HTR2A (0.71) | HTR2AHTR1ADRD2MAPT | |
| SCHEMBL8309219 | 0.76 | HTR1A (0.65) | HTR2AHTR1AACHESLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0747379-B1 | Derivatives of indole, indazole and benzisoxazole for the treatment of schizophrenia | ADIR (FR) | 1999-08-11 | — | — | EP | disclosed |
| EP-0747379-A1 | Derivatives of indole, indazole and benzisoxazole for the treatment of schizophrenia | ADIR ET COMPAGNIE (FR) | 1996-12-11 | — | — | EP | disclosed |