Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.30 |
| ▸ | F2 | P00734 | 1/20 | 0.30 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8303630 | 0.77 | ALOX5AP (0.38) | L3MBTL1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL8303628 | 0.77 | ALOX5AP (0.38) | L3MBTL1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL8308412 | 0.74 | P2RY1 (0.33) | P2RY1 | |
| SCHEMBL8304077 | 0.71 | P2RY1 (0.37) | KDM4EALDH1A1SMN1; SMN2P2RY1 | |
| SCHEMBL8304182 | 0.67 | ALDH1A1 (0.35) | L3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL8304186 | 0.67 | ALDH1A1 (0.35) | L3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL8303539 | 0.66 | KDM1A (0.39) | KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL8303541 | 0.66 | KDM1A (0.39) | KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL9405177 | 0.65 | SLC6A2 (0.42) | L3MBTL1 | |
| SCHEMBL7975735 | 0.62 | L3MBTL1 (0.37) | L3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832078-B1 | N-HYDROXYUREAS AS ANTIINFLAMMATORY AGENTS | PFIZER (US) | 1999-10-20 | — | — | EP | disclosed |
| EP-0832078-A1 | N-HYDROXYUREAS AS ANTIINFLAMMATORY AGENTS | PFIZER INC. (US) | 1998-04-01 | — | — | EP | disclosed |
| WO-1996040659-A1 | N-HYDROXYUREAS AS ANTIINFLAMMATORY AGENTS | PFIZER INC. (US) | 1996-12-19 | — | — | WO | disclosed |