Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY1 | P47900 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
| ▸ | KIF11 | P52732 | 1/20 | 0.31 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8304077 | 0.75 | P2RY1 (0.37) | P2RY1IMPDH2 | |
| SCHEMBL8306290 | 0.74 | L3MBTL1 (0.33) | P2RY1 | |
| SCHEMBL8303630 | 0.71 | ALOX5AP (0.38) | — | |
| SCHEMBL8303628 | 0.71 | ALOX5AP (0.38) | — | |
| SCHEMBL8303539 | 0.68 | KDM1A (0.39) | — | |
| SCHEMBL8303541 | 0.68 | KDM1A (0.39) | — | |
| SCHEMBL8304082 | 0.63 | P2RY1 (0.36) | P2RY1IMPDH2 | |
| SCHEMBL27848552 | 0.62 | HDAC3 (0.41) | IMPDH2 | |
| SCHEMBL27806570 | 0.62 | HDAC3 (0.41) | IMPDH2 | |
| SCHEMBL34460861 | 0.60 | TSHR (0.50) | P2RY1IMPDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832078-B1 | N-HYDROXYUREAS AS ANTIINFLAMMATORY AGENTS | PFIZER (US) | 1999-10-20 | — | — | EP | disclosed |