Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C2 | P52895 | 2/20 | 0.65 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.65 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.65 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | PKM | P14618 | 1/20 | 0.62 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.61 |
| ▸ | DHODH | Q02127 | 2/20 | 0.57 |
| ▸ | CASP6 | P55212 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | NPY1R | P25929 | 1/20 | 0.56 |
| ▸ | MC4R | P32245 | 1/20 | 0.56 |
| ▸ | NPY2R | P49146 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | CA4 | P22748 | 1/20 | 0.55 |
| ▸ | CA7 | P43166 | 1/20 | 0.55 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13401489 | 0.88 | ALDH1A1 (0.72) | AKR1C2AKR1C1AKR1C3MEN1KMT2A | |
| SCHEMBL1309081 | 0.82 | SMN1; SMN2 (0.70) | AKR1C2AKR1C1AKR1C3MEN1KMT2A | |
| SCHEMBL7722700 | 0.81 | ALDH1A1 (0.68) | MEN1KMT2AALDH1A1MAPTCYP1A2 | |
| SCHEMBL8303947 | 0.81 | ALDH1A1 (0.71) | MEN1KMT2AHCAR3CASP6ALDH1A1 | |
| SCHEMBL4092971 | 0.81 | KMT2A (0.71) | AKR1C2AKR1C1AKR1C3MEN1KMT2A | |
| SCHEMBL28558521 | 0.81 | KDM4E (0.72) | AKR1C2AKR1C1AKR1C3MEN1KMT2A | |
| SCHEMBL7717663 | 0.80 | ALDH1A1 (0.66) | MEN1KMT2AALDH1A1MAPTCYP1A2 | |
| SCHEMBL8305753 | 0.80 | SMN1; SMN2 (0.74) | AKR1C2AKR1C1AKR1C3MEN1KMT2A | |
| SCHEMBL8307686 | 0.80 | ALOX5 (0.68) | MEN1KMT2AHCAR3ALDH1A1MAPT | |
| SCHEMBL15679879 | 0.79 | MEN1 (0.62) | AKR1C2AKR1C1AKR1C3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934068-A1 | COMPOUNDS AND METHODS | SMITHKLINE BEECHAM CORPORATION (US) | 1999-08-11 | — | — | EP | disclosed |
| WO-1998009630-A1 | COMPOUNDS AND METHODS | SMITHKLINE BEECHAM CORPORATION (US) | 1998-03-12 | — | — | WO | disclosed |