Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.68 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 6/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | RORC | P51449 | 1/20 | 0.55 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8026664 | 0.89 | MAPT (0.67) | ALOX5CHEK1KMT2AMEN1MAPT | |
| SCHEMBL9232842 | 0.82 | ALOX5 (0.78) | ALOX5NPC1RAB9ACYP1A2CYP3A4 | |
| SCHEMBL8306313 | 0.80 | AKR1C2 (0.65) | CHEK1CYP1A2CYP2C9CYP2C19KMT2A | |
| SCHEMBL6900995 | 0.80 | CYP1A2 (0.63) | ALOX5NPC1RAB9ACYP1A2CYP3A4 | |
| SCHEMBL8305753 | 0.79 | SMN1; SMN2 (0.74) | NPC1RAB9ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL18992223 | 0.79 | ALOX5 (0.72) | ALOX5NPC1RAB9ACYP1A2CYP3A4 | |
| SCHEMBL21914836 | 0.78 | NPC1 (0.80) | ALOX5NPC1RAB9ACYP1A2CYP3A4 | |
| SCHEMBL8308004 | 0.78 | MEN1 (0.69) | CYP1A2CYP3A4CYP2C9CYP2C19KMT2A | |
| SCHEMBL8445659 | 0.78 | LMNA (0.71) | NPC1RAB9ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL12113016 | 0.78 | ALOX5 (0.73) | ALOX5NPC1RAB9ACYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934068-A1 | COMPOUNDS AND METHODS | SMITHKLINE BEECHAM CORPORATION (US) | 1999-08-11 | — | — | EP | disclosed |
| WO-1998009630-A1 | COMPOUNDS AND METHODS | SMITHKLINE BEECHAM CORPORATION (US) | 1998-03-12 | — | — | WO | disclosed |