Pyrazole

Pyrazole

SCHEMBL8306957

NC(=O)CO.c1cn[nH]c1

nearest known ligand 0.00

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⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyrazole SCHEMBL1129000 0.86
Propionamide SCHEMBL9349954 0.85 ALOX15 (0.30)
Pyrazole SCHEMBL28727019 0.84
Pyrazole SCHEMBL440249 0.84
Pyrazole SCHEMBL6009803 0.82
Pyrazole SCHEMBL28095827 0.82
Pyrazole SCHEMBL1724037 0.81
Oxamate SCHEMBL30882809 0.80 LDHA (0.41)
Pyrazole SCHEMBL27846756 0.79
Pyrazole SCHEMBL5064075 0.79 HCAR2 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-7304747-A None JP disclosed
CN-101448397-B Selective benzylamine derivatives and their use as cholesteryl ester transfer protein inhibitors REDDYS LAB LTD DR 2013-04-24 CN disclosed
CN-101448397-A Selective benzylamine derivatives and their use as cholesteryl ester transfer protein inhibitors REDDY US THERAPEUTICS INC (US) 2009-06-03 CN disclosed
US-5998334-A Pyrazole compounds, processes for their production and herbicides containing them ISHIHARA SANGYO KAISHA LTD. (JP) 1999-12-07 US disclosed
EP-0900205-A1 PYRAZOLE COMPOUNDS, PROCESSES FOR THEIR PRODUCTION AND HERBICIDES CONTAINING THEM ISHIHARA SANGYO KAISHA, LTD. (JP) 1999-03-10 EP disclosed
WO-1997041106-A1 PYRAZOLE COMPOUNDS, PROCESSES FOR THEIR PRODUCTION AND HERBICIDES CONTAINING THEM ISHIHARA SANGYO KAISHA LTD. (JP) 1997-11-06 WO disclosed
JP-H07304747-A 3,5-DICHLORO-4-CYANO-1-METHYLPYRAZOLE AND PRODUCTION THEREOF NISSAN CHEM IND LTD 1995-11-21 JP disclosed