Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6541931 | 0.71 | GRM8 (0.30) | — | |
| SCHEMBL8133012 | 0.71 | GRM8 (0.30) | — | |
| SCHEMBL11785262 | 0.71 | GRM8 (0.30) | — | |
| SCHEMBL4653448 | 0.71 | GRM8 (0.30) | — | |
| SCHEMBL6541949 | 0.71 | GRM8 (0.30) | — | |
| SCHEMBL16149649 | 0.66 | PRKCA (0.31) | — | |
| SCHEMBL18175953 | 0.64 | SMN1; SMN2 (0.36) | LMNATSHR | |
| SCHEMBL1634054 | 0.63 | LMNA (0.39) | LMNATSHR | |
| SCHEMBL7324781 | 0.61 | SMN1; SMN2 (0.31) | TSHRGAA | |
| SCHEMBL1634637 | 0.61 | LMNA (0.38) | LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0646116-B1 | PROCESS AND INTERMEDIATES FOR BIS-AZA-BICYCLIC ANXIOLYTIC AGENTS | PFIZER (US) | 1999-10-13 | — | — | EP | disclosed |
| US-5719286-A | Process and intermediates for bis-aza-bicyclic anxiolytic agents | PFIZER INC. (US) | 1998-02-17 | — | — | US | disclosed |
| EP-0646116-A1 | PROCESS AND INTERMEDIATES FOR BIS-AZA-BICYCLIC ANXIOLYTIC AGENTS | PFIZER INC. (US) | 1995-04-05 | — | — | EP | disclosed |
| WO-1993025552-A1 | PROCESS AND INTERMEDIATES FOR BIS-AZA-BICYCLIC ANXIOLYTIC AGENTS | PFIZER INC. (US) | 1993-12-23 | — | — | WO | disclosed |