Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM8 | O00222 | 1/20 | 0.30 |
| ▸ | GRM6 | O15303 | 1/20 | 0.30 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.30 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6541949 | 1.00 | GRM8 (0.30) | GRM8GRM6GRM2GRM3 | |
| SCHEMBL11785262 | 1.00 | GRM8 (0.30) | GRM8GRM6GRM2GRM3 | |
| SCHEMBL6541931 | 1.00 | GRM8 (0.30) | GRM8GRM6GRM2GRM3 | |
| SCHEMBL8133012 | 1.00 | GRM8 (0.30) | GRM8GRM6GRM2GRM3 | |
| SCHEMBL7502610 | 0.71 | — | — | |
| SCHEMBL6543466 | 0.71 | — | — | |
| SCHEMBL8307214 | 0.71 | LMNA (0.33) | — | |
| SCHEMBL6542872 | 0.65 | — | — | |
| SCHEMBL8611928 | 0.58 | TSHR (0.35) | — | |
| SCHEMBL30803050 | 0.57 | GRM2 (0.31) | GRM8GRM6GRM2GRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210107855-A1 | HYDROXYCITRIC ACID METAL HETEROCYCLIC COMPOUNDS WITH COVALENT CHARACTERISTICS | GLYKON TECHNOLOGIES GROUP, LLC (US) | 2021-04-15 | — | — | US | disclosed |
| US-7741370-B2 | Double salts of (−)-hydroxycitric acid and a process for preparing the same | LAILA IMPEX (IN) | 2010-06-22 | — | — | US | disclosed |
| US-7741370-B2 | Double salts of (−)-hydroxycitric acid and a process for preparing the same | LAILA IMPEX (IN) | 2010-06-22 | — | — | US | disclosed |
| EP-1602354-B1 | Use of polyglutamic acid or its salts | MEIJI SEIKA KAISHA (JP) | 2008-11-05 | — | — | EP | disclosed |
| EP-1604647-B1 | Cosmetic composition containing polyorganosiloxane-containing epsilon-polylysine polymer, and polyhydric alcohol, and production thereof | CHISSO CORP (JP) | 2008-05-07 | — | — | EP | disclosed |
| US-7208615-B2 | Triple mineral salts of (-)-hydroxycitric acid and processes for preparing the same | LAILA IMPEX (IN) | 2007-04-24 | — | — | US | disclosed |
| US-7208615-B2 | Triple mineral salts of (-)-hydroxycitric acid and processes for preparing the same | LAILA IMPEX (IN) | 2007-04-24 | — | — | US | disclosed |
| US-20060165636-A1 | Hair treatment composition and hair cosmetic for damaged hair | MEIJI SEIKA KAISHA, LTD. (JP) | 2006-07-27 | — | — | US | disclosed |
| US-20060018867-A1 | Cosmetic composition and production thereof | ICHIMARU PHARCOS CO., LTD | 2006-01-26 | — | — | US | disclosed |
| EP-1604647-A1 | Cosmetic composition containing polyorganosiloxane-containing epsilon-polylysine polymer, and polyhydric alcohol, and production thereof | Ichimaru Pharcos Co., Ltd. (JP) | 2005-12-14 | — | — | EP | disclosed |
| EP-1602354-A1 | HAIR TREATMENT COMPOSITION AND HAIR COSMETIC FOR DAMAGED HAIR | Meiji Seika Kaisha, Ltd. (JP) | 2005-12-07 | — | — | EP | disclosed |
| US-20040185069-A1 | Hydroxycitric acid derivatives for body slimming and tone firming compositions | GUPTA SHYAM K (US) | 2004-09-23 | — | — | US | disclosed |
| JP-2000154134-A | COSMETIC | NARIS COSMETICS CO LTD | 2000-06-06 | — | — | JP | disclosed |
| US-4028397-A | ANTIOBESITY AGENTS | HOFFMANN-LA ROCHE INC. (US) | 1977-06-07 | — | — | US | disclosed |
| US-4007208-A | ANTIOBESITY, ANTILIPID | HOFFMANN-LA ROCHE INC. (US) | 1977-02-08 | — | — | US | disclosed |
| US-4006166-A | ANTI-OBESITY, LIPID ABNORMALITIES | HOFFMANN-LA ROCHE INC. (US) | 1977-02-01 | — | — | US | disclosed |
| US-3994927-A | ANTIOBESITY, INHIBIT SYNTHESIS OF FATTY ACIDS | HOFFMANN-LA ROCHE INC. (US) | 1976-11-30 | — | — | US | disclosed |
| US-3993668-A | ANTIOBESITY AGENTS | HOFFMANN-LA ROCHE INC. (US) | 1976-11-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060165636-A1 | Hair treatment composition and hair cosmetic for damaged hair | CUTA, COL14A1, PRKDC | GRM8 1038/4885GRM6 640/4885GRM2 365/4885 |
| US-20060018867-A1 | Cosmetic composition and production thereof | CUTA, PARG, TYR | GRM8 4152/4885GRM6 4839/4885GRM2 4774/4885 |
| US-20210107855-A1 | HYDROXYCITRIC ACID METAL HETEROCYCLIC COMPOUNDS WITH COVALENT CHARACTERISTICS | HCAR1, HCAR2, HCAR3 | GRM8 2846/4885GRM6 2376/4885GRM2 2161/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.