Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 4/20 | 0.41 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HGFAC | Q04756 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8311914 | 0.81 | KMT2A (0.39) | SLC6A2SLC6A4SLC6A3POLBTDP1 | |
| SCHEMBL8311548 | 0.80 | DRD2 (0.46) | POLBALDH1A1 | |
| SCHEMBL6359097 | 0.77 | TAS1R3 (0.40) | HSD17B10SLC6A2SLC6A4SLC6A3POLB | |
| SCHEMBL6363447 | 0.75 | KMT2A (0.43) | HSD17B10SLC6A2SLC6A4SLC6A3MAPK1 | |
| SCHEMBL28752620 | 0.74 | POLB (0.41) | POLBTDP1NPSR1HTTMAPT | |
| SCHEMBL8308233 | 0.72 | CHRM4 (0.47) | POLBNPSR1KDM4EHTTMAPT | |
| SCHEMBL8312961 | 0.72 | HSP90AA1 (0.46) | POLBNPSR1KDM4EMAPTMEN1 | |
| SCHEMBL7531672 | 0.71 | HSD17B10 (0.56) | HSD17B10POLBPTPN2PTPN1TDP1 | |
| SCHEMBL10469676 | 0.69 | HSP90AA1 (0.44) | KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL8744123 | 0.69 | HSD17B10 (0.57) | HSD17B10POLBTDP1NPSR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004087124-A1 | COMPOUNDS HAVING SEROTONIN 5-HT17 RECEPTOR ANTAGONIST ACTIVITY AND MUSCARINIC M4 RECEPTOR AGONIST ACTIVITY AND THEIR USE IN THE TREATMENT OF PSYCHOTIC DISORDERS | MITSUBISHI PHARMA CORPORATION (JP) | 2004-10-14 | — | — | WO | disclosed |