Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | KDM5C | P41229 | 2/20 | 0.34 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.34 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.33 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.32 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9679040 | 0.77 | MAPT (0.34) | TSHRCYP1A2LMNATDP1HPGD | |
| SCHEMBL9912192 | 0.73 | ALDH1A1 (0.40) | TSHRLMNAKMT2ANAALAD2KDM4E | |
| SCHEMBL8309477 | 0.72 | TSHR (0.44) | TSHRCYP1A2LMNAKMT2AHSD17B10 | |
| SCHEMBL23897409 | 0.71 | LMNA (0.33) | LMNAKMT2AHPGD | |
| SCHEMBL8308703 | 0.71 | TSHR (0.48) | TSHRCYP1A2LMNAKMT2AHSD17B10 | |
| SCHEMBL2859890 | 0.69 | PHF8 (0.50) | LMNANAALAD2EGLN1KDM4EKDM5C | |
| SCHEMBL668605 | 0.67 | — | — | |
| SCHEMBL5893326 | 0.67 | LMNA (0.56) | TSHRLMNAHPGDHDAC2MAPT | |
| SCHEMBL6891006 | 0.67 | TSHR (0.42) | TSHRCYP1A2LMNAKMT2AHSD17B10 | |
| SCHEMBL26234067 | 0.67 | TSHR (0.42) | TSHRCYP1A2LMNAKMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0903346-A1 | SYDNONE IMINE DERIVATIVES | Chugai Seiyaku Kabushiki Kaisha (JP) | 1999-03-24 | — | — | EP | disclosed |