Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.39 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 6/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.37 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | KDM5C | P41229 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14776802 | 0.84 | GPR84 (0.47) | TSHRTDP1KMT2AHSD17B10LMNA | |
| SCHEMBL27271477 | 0.79 | — | — | |
| SCHEMBL8310501 | 0.77 | HDAC3 (0.46) | KMT2AHSD17B10HDAC3HDAC1HDAC2 | |
| SCHEMBL17724885 | 0.77 | — | — | |
| SCHEMBL9679774 | 0.76 | — | — | |
| SCHEMBL4878677 | 0.76 | ALDH1A1 (0.50) | TDP1HSD17B10LMNAHDAC3HDAC1 | |
| SCHEMBL8801947 | 0.76 | — | — | |
| SCHEMBL28607111 | 0.75 | ALDH1A1 (0.41) | TSHRCYP1A2TDP1KMT2AHSD17B10 | |
| SCHEMBL9420088 | 0.74 | — | — | |
| SCHEMBL8307853 | 0.72 | TSHR (0.42) | TSHRCYP1A2TDP1KMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2576502-B1 | NOVEL CHELATOR AND USE THEREOF | CYTIVA BIOPROCESS R & D AB (SE) | 2020-08-05 | — | — | EP | disclosed |
| EP-2576502-B1 | NOVEL CHELATOR AND USE THEREOF | CYTIVA BIOPROCESS R & D AB (SE) | 2020-08-05 | — | — | EP | disclosed |
| US-10662261-B2 | Chelator and use thereof | GE HEALTHCARE BIOPROCESS R&D AB (SE) | 2020-05-26 | — | — | US | disclosed |
| US-10662261-B2 | Chelator and use thereof | GE HEALTHCARE BIOPROCESS R&D AB (SE) | 2020-05-26 | — | — | US | disclosed |
| US-20180223003-A1 | Novel Chelator and Use Thereof | CYTIVA BIOPROCESS R&D AB (SE) | 2018-08-09 | — | — | US | disclosed |
| US-20180223003-A1 | Novel Chelator and Use Thereof | CYTIVA BIOPROCESS R&D AB (SE) | 2018-08-09 | — | — | US | disclosed |
| US-20180223003-A1 | Novel Chelator and Use Thereof | CYTIVA BIOPROCESS R&D AB (SE) | 2018-08-09 | — | — | US | disclosed |
| US-9944722-B2 | Chelator and use thereof | GE HEALTHCARE BIOPROCESS R&D AB (SE) | 2018-04-17 | — | — | US | disclosed |
| US-9944722-B2 | Chelator and use thereof | GE HEALTHCARE BIOPROCESS R&D AB (SE) | 2018-04-17 | — | — | US | disclosed |
| US-9944722-B2 | Chelator and use thereof | GE HEALTHCARE BIOPROCESS R&D AB (SE) | 2018-04-17 | — | — | US | disclosed |
| US-20130072638-A1 | NOVEL CHELATOR AND USE THEREOF | GE HEALTHCARE BIO-SCIENCES AB (SE) | 2013-03-21 | — | — | US | disclosed |
| US-20130072638-A1 | NOVEL CHELATOR AND USE THEREOF | GE HEALTHCARE BIO-SCIENCES AB (SE) | 2013-03-21 | — | — | US | disclosed |
| US-20130072638-A1 | NOVEL CHELATOR AND USE THEREOF | GE HEALTHCARE BIO-SCIENCES AB (SE) | 2013-03-21 | — | — | US | disclosed |
| WO-2011152782-A1 | NOVEL CHELATOR AND USE THEREOF | GE HEALTHCARE BIO-SCIENCES AB (SE) | 2011-12-08 | — | — | WO | disclosed |
| EP-0903346-A1 | SYDNONE IMINE DERIVATIVES | Chugai Seiyaku Kabushiki Kaisha (JP) | 1999-03-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180223003-A1 | Novel Chelator and Use Thereof | SPR, ATIC, PHPT1 | TSHR 637/4885CYP1A2 4755/4885TDP1 2755/4885 |
| US-10662261-B2 | Chelator and use thereof | ATIC, PHPT1, ADA | TSHR 1084/4885CYP1A2 4771/4885TDP1 2302/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.