Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.47 |
| ▸ | EGFR | P00533 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | KHK | P50053 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5357967 | 0.78 | KMT2A (0.57) | MEN1KMT2AMAPTP2RX7EGFR | |
| SCHEMBL9403797 | 0.71 | MPO (0.40) | MAPTEGFR | |
| SCHEMBL1548694 | 0.71 | ALDH1A1 (0.54) | MEN1KMT2AMAPTGAAPOLB | |
| SCHEMBL9617964 | 0.71 | KCNQ2 (0.44) | MEN1KMT2AMAPTTP53POLB | |
| SCHEMBL8307878 | 0.70 | HTT (0.54) | MAPTEGFRTSHR | |
| SCHEMBL17085318 | 0.70 | GALR3 (0.54) | EGFR | |
| SCHEMBL2461566 | 0.70 | EGFR (0.68) | MEN1KMT2AEGFRGAA | |
| SCHEMBL13064098 | 0.69 | SELE (0.35) | POLB | |
| SCHEMBL18951516 | 0.69 | MEN1 (0.52) | MEN1KMT2AMAPTP2RX7EGFR | |
| SCHEMBL3802570 | 0.69 | PIP4K2C (0.53) | MEN1KMT2AMAPTEGFRGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0555388-B1 | INSECTICIDAL, ACARICIDAL AND FUNGICIDAL AMINOPYRIMIDINES | DU PONT (US) | 1999-01-27 | — | — | EP | disclosed |
| US-5378708-A | Agricultural pesticides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1995-01-03 | — | — | US | disclosed |
| EP-0555388-A1 | INSECTICIDAL, ACARICIDAL AND FUNGICIDAL AMINOPYRIMIDINES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-08-18 | — | — | EP | disclosed |
| WO-1992008704-A1 | INSECTICIDAL, ACARICIDAL AND FUNGICIDAL AMINOPYRIMIDINES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-05-29 | — | — | WO | disclosed |