Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | CASP6 | P55212 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8305753 | 0.85 | SMN1; SMN2 (0.74) | ALDH1A1SMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL8521515 | 0.83 | MEN1 (0.60) | ALDH1A1SMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL6814247 | 0.76 | MEN1 (0.70) | ALDH1A1SMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL8303947 | 0.76 | ALDH1A1 (0.71) | ALDH1A1KDM4ESMN1; SMN2MAPTMEN1 | |
| SCHEMBL10599217 | 0.75 | MEN1 (0.64) | ALDH1A1SMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL8302750 | 0.75 | CASP6 (0.48) | ALDH1A1SMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL8760125 | 0.75 | CASP6 (0.62) | ALDH1A1SMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL22734863 | 0.75 | CASP6 (0.62) | ALDH1A1SMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL11654108 | 0.74 | CASP6 (0.67) | ALDH1A1MAPTMEN1KMT2APOLB | |
| SCHEMBL606248 | 0.74 | ALDH1A1 (0.80) | ALDH1A1KDM4ESMN1; SMN2MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934068-A1 | COMPOUNDS AND METHODS | SMITHKLINE BEECHAM CORPORATION (US) | 1999-08-11 | — | — | EP | disclosed |
| WO-1998009630-A1 | COMPOUNDS AND METHODS | SMITHKLINE BEECHAM CORPORATION (US) | 1998-03-12 | — | — | WO | disclosed |