Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMO | Q99835 | 13/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MTTP | P55157 | 8/20 | 0.36 |
| ▸ | APOB | P04114 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8309546 | 0.87 | FYN (0.47) | SMOMTTPAPOB | |
| SCHEMBL8309245 | 0.85 | SMO (0.32) | SMOMTTPAPOB | |
| SCHEMBL8309596 | 0.84 | SMO (0.38) | SMOMEN1KMT2AMTTPAPOB | |
| SCHEMBL8309243 | 0.84 | MTTP (0.45) | SMOMEN1KMT2AMTTPAPOB | |
| SCHEMBL8306217 | 0.84 | SMO (0.40) | SMOMTTPAPOB | |
| SCHEMBL8307723 | 0.84 | DRD2 (0.32) | SMOMTTPAPOB | |
| SCHEMBL8308398 | 0.82 | KMT2A (0.37) | MEN1KMT2A | |
| SCHEMBL8309952 | 0.81 | SMO (0.38) | SMOMTTPAPOB | |
| SCHEMBL8306272 | 0.81 | SMO (0.38) | SMOMEN1KMT2AMTTPAPOB | |
| SCHEMBL8310235 | 0.80 | GRIN2B (0.49) | SMOMTTPAPOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0759027-B1 | BICYCLIC AMIDINE DERIVATIVES AS INHIBITORS OF NITRIC OXIDE SYNTHETASE | ASTRA AB (SE) | 1999-08-04 | — | — | EP | claimed |