Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 1/20 | 0.47 |
| ▸ | MTTP | P55157 | 2/20 | 0.45 |
| ▸ | APOB | P04114 | 1/20 | 0.45 |
| ▸ | SMO | Q99835 | 7/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8309243 | 0.94 | MTTP (0.45) | FYNMTTPAPOBSMOHDAC1 | |
| SCHEMBL8310235 | 0.92 | GRIN2B (0.49) | FYNMTTPAPOBSMOGRIN2B | |
| SCHEMBL8309596 | 0.91 | SMO (0.38) | FYNMTTPAPOBSMOHDAC1 | |
| SCHEMBL8306217 | 0.90 | SMO (0.40) | FYNMTTPAPOBSMO | |
| SCHEMBL8309952 | 0.89 | SMO (0.38) | FYNMTTPAPOBSMO | |
| SCHEMBL8306272 | 0.89 | SMO (0.38) | FYNMTTPAPOBSMO | |
| SCHEMBL8307994 | 0.87 | SMO (0.39) | MTTPAPOBSMO | |
| SCHEMBL8307723 | 0.86 | DRD2 (0.32) | MTTPAPOBSMORAB9ADRD2 | |
| SCHEMBL8305839 | 0.82 | GRIN2B (0.38) | GRIN2BDRD2 | |
| SCHEMBL8309245 | 0.82 | SMO (0.32) | MTTPAPOBSMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0759027-B1 | BICYCLIC AMIDINE DERIVATIVES AS INHIBITORS OF NITRIC OXIDE SYNTHETASE | ASTRA AB (SE) | 1999-08-04 | — | — | EP | claimed |