Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMO | Q99835 | 11/20 | 0.40 |
| ▸ | MTTP | P55157 | 7/20 | 0.37 |
| ▸ | APOB | P04114 | 2/20 | 0.37 |
| ▸ | FYN | P06241 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8309546 | 0.90 | FYN (0.47) | SMOMTTPAPOBFYN | |
| SCHEMBL8309952 | 0.90 | SMO (0.38) | SMOMTTPAPOBFYN | |
| SCHEMBL8306272 | 0.90 | SMO (0.38) | SMOMTTPAPOBFYN | |
| SCHEMBL8309596 | 0.89 | SMO (0.38) | SMOMTTPAPOBFYN | |
| SCHEMBL8309243 | 0.85 | MTTP (0.45) | SMOMTTPAPOBFYN | |
| SCHEMBL8307994 | 0.84 | SMO (0.39) | SMOMTTPAPOB | |
| SCHEMBL8310235 | 0.83 | GRIN2B (0.49) | SMOMTTPAPOBFYN | |
| SCHEMBL8305839 | 0.83 | GRIN2B (0.38) | — | |
| SCHEMBL8307723 | 0.83 | DRD2 (0.32) | SMOMTTPAPOB | |
| SCHEMBL8185945 | 0.78 | SMO (0.44) | SMOMTTPAPOBFYNACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0759027-B1 | BICYCLIC AMIDINE DERIVATIVES AS INHIBITORS OF NITRIC OXIDE SYNTHETASE | ASTRA AB (SE) | 1999-08-04 | — | — | EP | claimed |