Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.33 |
| ▸ | TUBB1 | Q9H4B7 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6596199 | 0.85 | L3MBTL1 (0.43) | L3MBTL1ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL6596708 | 0.73 | L3MBTL1 (0.40) | L3MBTL1ALDH1A1KMT2ALMNAMAPK1 | |
| SCHEMBL6596594 | 0.73 | TACR2 (0.48) | PDE4D | |
| SCHEMBL6595201 | 0.72 | TACR2 (0.50) | — | |
| SCHEMBL6597387 | 0.71 | LMNA (0.45) | SMN1; SMN2ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL6596311 | 0.71 | SMN1; SMN2 (0.40) | SMN1; SMN2L3MBTL1ALDH1A1GAATUBB1 | |
| SCHEMBL6594371 | 0.70 | ACKR3 (0.45) | SMN1; SMN2L3MBTL1ALDH1A1PDE4DMEN1 | |
| SCHEMBL6594635 | 0.70 | L3MBTL1 (0.39) | L3MBTL1GAAPDE4DKMT2ATUBB1 | |
| SCHEMBL6595256 | 0.69 | TUBB4A (0.42) | ALDH1A1TDP1MEN1KMT2ARAB9A | |
| SCHEMBL8307825 | 0.68 | L3MBTL1 (0.39) | SMN1; SMN2L3MBTL1ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0888338-A1 | NOVEL SUBSTITUTED N-METHYL-N-(4-(4-(1H-BENZIMIDAZOL-2-YL) 1,4]DIAZEPAN-1-YL)-2-(ARYL)BUTYL)BENZAMIDES USEFUL FOR THE TREATMENT OF ALLERGIC DISEASES | HOECHST MARION ROUSSEL, INC. (US) | 1999-01-07 | — | — | EP | disclosed |
| WO-1997030991-A1 | NOVEL SUBSTITUTED N-METHYL-N-(4-(4-(1H-BENZIMIDAZOL-2-YL)[1,4]DIAZEPAN-1-YL)-2-(ARYL)BUTYL)BENZAMIDES USEFUL FOR THE TREATMENT OF ALLERGIC DISEASES | HOECHST MARION ROUSSEL, INC. (US) | 1997-08-28 | — | — | WO | disclosed |