Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 4/20 | 0.74 |
| ▸ | HTR6 | P50406 | 5/20 | 0.70 |
| ▸ | MTNR1A | P48039 | 6/20 | 0.62 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.62 |
| ▸ | NQO2 | P16083 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SYK | P43405 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8307407 | 0.91 | ADRB2 (0.70) | ADRB2HTR6MTNR1AMTNR1BNQO2 | |
| SCHEMBL12185393 | 0.86 | ADRB2 (0.76) | ADRB2HTR6MTNR1AMTNR1BNQO2 | |
| SCHEMBL1130016 | 0.85 | ADRB2 (1.00) | ADRB2HTR6MTNR1AMTNR1BNQO2 | |
| SCHEMBL8306890 | 0.85 | ADRB2 (0.74) | ADRB2HTR6MTNR1AMTNR1BNQO2 | |
| Hydrochloric Acid SCHEMBL7680700 | 0.84 | ADRB2 (0.97) | ADRB2HTR6MTNR1AMTNR1BNQO2 | |
| SCHEMBL13888101 | 0.83 | ADRB2 (0.70) | ADRB2HTR6MTNR1AMTNR1BNQO2 | |
| SCHEMBL20307221 | 0.82 | HTR6 (1.00) | ADRB2HTR6MTNR1AMTNR1BNQO2 | |
| SCHEMBL8304470 | 0.82 | ADRB2 (0.70) | ADRB2HTR6MTNR1AMTNR1BNQO2 | |
| SCHEMBL32669223 | 0.81 | ADRB2 (0.68) | ADRB2HTR6MTNR1AMTNR1BNQO2 | |
| SCHEMBL18509701 | 0.80 | MTNR1A (0.67) | ADRB2HTR6MTNR1AMTNR1BNQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0747379-B1 | Derivatives of indole, indazole and benzisoxazole for the treatment of schizophrenia | ADIR (FR) | 1999-08-11 | — | — | EP | disclosed |
| US-5703070-A | PSYCHOLOGICAL DISORDERS | ADIR ET COMPAGNIE (FR) | 1997-12-30 | — | — | US | disclosed |
| EP-0747379-A1 | Derivatives of indole, indazole and benzisoxazole for the treatment of schizophrenia | ADIR ET COMPAGNIE (FR) | 1996-12-11 | — | — | EP | disclosed |