Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 3/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | CYP1A1 | P04798 | 8/20 | 0.40 |
| ▸ | CYP1B1 | Q16678 | 8/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 7/20 | 0.40 |
| ▸ | TERT | O14746 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8304148 | 0.79 | DYRK1A (0.49) | PTGS2ALDH1A1HPGDCYP3A4CYP1A1 | |
| SCHEMBL30598448 | 0.77 | ALDH1A1 (0.43) | ALDH1A1HPGDCYP3A4MAPTCYP2C9 | |
| SCHEMBL4574807 | 0.77 | ALDH1A1 (0.43) | ALDH1A1HPGDCYP3A4MAPTCYP2C9 | |
| SCHEMBL8429377 | 0.76 | ALDH1A1 (0.39) | PTGS1PTGS2ALDH1A1HPGDCYP3A4 | |
| SCHEMBL8308046 | 0.76 | MAOB (0.52) | PTGS1PTGS2ALDH1A1CYP3A4MAPT | |
| SCHEMBL8307482 | 0.73 | AKT1 (0.56) | PTGS1PTGS2HPGDMAPTCYP1A1 | |
| SCHEMBL8309333 | 0.72 | CYP1B1 (0.57) | PTGS1ALDH1A1HPGDCYP3A4MAPT | |
| SCHEMBL8431096 | 0.71 | ALDH1A1 (0.39) | PTGS1PTGS2ALDH1A1HPGDCYP3A4 | |
| SCHEMBL8305036 | 0.70 | MAPT (0.59) | CYP3A4MAPTCYP2C9CYP2C19CYP1A1 | |
| SCHEMBL8427330 | 0.69 | PTPN1 (0.39) | PTGS1PTGS2ALDH1A1HPGDCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0709383-B1 | Diosmetin derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 1999-12-15 | — | — | EP | disclosed |
| US-5629339-A | CHRONIC VENOUS INSUFFICIENCY | ADIR ET COMPAGNIE (FR) | 1997-05-13 | — | — | US | disclosed |
| EP-0709383-A1 | Diosmetin derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1996-05-01 | — | — | EP | disclosed |