Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | TNKS | O95271 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | HTR6 | P50406 | 2/20 | 0.44 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.44 |
| ▸ | HTR3B | O95264 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | NCF1 | P14598 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | HTR1D | P28221 | 1/20 | 0.44 |
| ▸ | HTR1B | P28222 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR7 | P34969 | 1/20 | 0.44 |
| ▸ | MTOR | P42345 | 1/20 | 0.44 |
| ▸ | HTR3A | P46098 | 1/20 | 0.44 |
| ▸ | HTR5A | P47898 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL138181 | 0.77 | KEAP1 (0.44) | TNKSHTR6KDM4EKMT2AMEN1 | |
| SCHEMBL29557633 | 0.77 | KEAP1 (0.44) | TNKSHTR6KDM4EKMT2AMEN1 | |
| SCHEMBL148918 | 0.76 | TNKS (0.42) | POLBTNKSHSD17B10CYP1A2ALDH1A1 | |
| SCHEMBL2750210 | 0.76 | MEN1 (0.56) | IDH1POLBHSD17B10HTR6CYP1A2 | |
| SCHEMBL4543332 | 0.76 | DDB1 (0.50) | P2RX7MAPTKMT2AMEN1 | |
| SCHEMBL3361698 | 0.76 | MGLL (0.43) | TNKSKDM4EP2RX7KMT2AGSK3A | |
| SCHEMBL8502875 | 0.76 | MGLL (0.43) | IDH1TNKSHTR6KDM4EP2RX7 | |
| SCHEMBL14899249 | 0.76 | GAA (0.42) | POLBTNKSKDM4EKMT2AMEN1 | |
| SCHEMBL7823337 | 0.75 | KEAP1 (0.42) | TNKSHSD17B10HTR6HTR1AHTR1D | |
| SCHEMBL7814732 | 0.75 | KEAP1 (0.46) | POLBHSD17B10TSHRALDH1A1P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0425209-B1 | Naphthyloxazolidone derivatives | TANABE SEIYAKU CO (JP) | 1995-05-10 | — | — | EP | claimed |
| US-5332754-A | Antidepressant | TANABE SEIYAKU CO., LTD. (JP) | 1994-07-26 | — | — | US | claimed |
| US-5182296-A | Antidepressants | TANABE SEIYAKY CO., LTD. (JP) | 1993-01-26 | — | — | US | claimed |
| EP-0425209-A2 | Naphthyloxazolidone derivatives | TANABE SEIYAKU CO., LTD. (JP) | 1991-05-02 | — | — | EP | claimed |
| JP-10226646-A | — | — | None | — | — | JP | disclosed |
| JP-10218772-A | — | — | None | — | — | JP | disclosed |
| JP-5155772-A | — | — | None | — | — | JP | disclosed |
| EP-0835254-B1 | OXAZOLIDINONE DERIVATIVES, THEIR PREPARATION AND THERAPEUTICAL USE | SYNTHELABO (FR) | 1999-09-01 | — | — | EP | disclosed |
| JP-H10226646-A | THERAPEUTIC AGENT OF PARKINSONISM | TANABE SEIYAKU CO LTD | 1998-08-25 | — | — | JP | disclosed |
| JP-H10218772-A | PREVENTIVE AND THERAPEUTIC AGENT FOR HYPOBULIA AND LOWERING OF SPONTANEITY DUE TO CEREBROVASCULAR ACCIDENT OR DEPRESSION SYSTEM | TANABE SEIYAKU CO LTD | 1998-08-18 | — | — | JP | disclosed |
| EP-0530811-B1 | 5-Substituted 2-oxazolidinones | NIPPON PAINT CO LTD (JP) | 1997-06-25 | — | — | EP | disclosed |
| EP-0425209-B1 | Naphthyloxazolidone derivatives | TANABE SEIYAKU CO (JP) | 1995-05-10 | — | — | EP | disclosed |
| US-5332754-A | Antidepressant | TANABE SEIYAKU CO., LTD. (JP) | 1994-07-26 | — | — | US | disclosed |
| US-5332754-A | Antidepressant | TANABE SEIYAKU CO., LTD. (JP) | 1994-07-26 | — | — | US | disclosed |
| JP-H05155772-A | ANTIDEPRESSANT | TANABE SEIYAKU CO LTD | 1993-06-22 | — | — | JP | disclosed |
| US-5182296-A | Antidepressants | TANABE SEIYAKY CO., LTD. (JP) | 1993-01-26 | — | — | US | disclosed |
| US-5182296-A | Antidepressants | TANABE SEIYAKY CO., LTD. (JP) | 1993-01-26 | — | — | US | disclosed |
| EP-0425209-A2 | Naphthyloxazolidone derivatives | TANABE SEIYAKU CO., LTD. (JP) | 1991-05-02 | — | — | EP | disclosed |
| EP-0425209-A2 | Naphthyloxazolidone derivatives | TANABE SEIYAKU CO., LTD. (JP) | 1991-05-02 | — | — | EP | disclosed |
| EP-0425209-A2 | Naphthyloxazolidone derivatives | TANABE SEIYAKU CO., LTD. (JP) | 1991-05-02 | — | — | EP | disclosed |