Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | POLH | Q9Y253 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8304673 | 0.92 | BRD4 (0.40) | MAPTKDM4ECYP3A4HSD17B10ALDH1A1 | |
| SCHEMBL8307532 | 0.91 | L3MBTL1 (0.39) | MAPTHPGDKDM4ECYP3A4ALDH1A1 | |
| SCHEMBL8306914 | 0.89 | CYP1B1 (0.43) | MAPTCYP3A4ALDH1A1SMN1; SMN2KCNA5 | |
| SCHEMBL8306597 | 0.83 | ABCB1 (0.42) | KDM4EALDH1A1PPARGMEN1KMT2A | |
| SCHEMBL8309735 | 0.83 | KDM4E (0.39) | MAPTKDM4EPOLBPOLH | |
| SCHEMBL8310185 | 0.83 | MAOB (0.41) | MAPTKDM4ECYP3A4HSD17B10ALDH1A1 | |
| SCHEMBL8308992 | 0.82 | MAOB (0.39) | MAPTKDM4ECYP3A4HSD17B10ALDH1A1 | |
| SCHEMBL8859601 | 0.81 | BRD4 (0.39) | MAPTHPGDKDM4ECYP3A4HSD17B10 | |
| SCHEMBL8859603 | 0.81 | BRD4 (0.39) | MAPTHPGDKDM4ECYP3A4HSD17B10 | |
| SCHEMBL8309125 | 0.81 | CYP1B1 (0.52) | MAPTCYP3A4ALDH1A1SMN1; SMN2KCNA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0709383-B1 | Diosmetin derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 1999-12-15 | — | — | EP | disclosed |
| US-5629339-A | CHRONIC VENOUS INSUFFICIENCY | ADIR ET COMPAGNIE (FR) | 1997-05-13 | — | — | US | disclosed |
| EP-0709383-A1 | Diosmetin derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1996-05-01 | — | — | EP | disclosed |