Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 7/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.49 |
| ▸ | NPY1R | P25929 | 1/20 | 0.49 |
| ▸ | NPY2R | P49146 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8304545 | 0.83 | KMT2A (0.54) | KMT2AMEN1MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL9598761 | 0.80 | CYP1A2 (0.69) | KMT2AMAPTSMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL658878 | 0.78 | HTT (0.61) | KMT2AMEN1MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL8303937 | 0.76 | SMN1; SMN2 (0.61) | KMT2AMEN1MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL22130133 | 0.74 | ALDH1A1 (0.59) | KMT2AMAPTSMN1; SMN2ALDH1A1HTT | |
| SCHEMBL14267744 | 0.74 | ALOX5 (0.49) | KMT2AMEN1MAPTALDH1A1HTT | |
| SCHEMBL12344276 | 0.73 | SMN1; SMN2 (0.66) | KMT2AMEN1MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL4301852 | 0.73 | KMT2A (0.54) | KMT2AMEN1MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL2187627 | 0.73 | NPC1 (0.80) | KMT2AMEN1MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL8358751 | 0.72 | KMT2A (0.67) | KMT2AMEN1ALDH1A1HTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0609441-B1 | Oxazolidone derivatives as monoamine oxidase inhibitors | EISAI CO LTD (JP) | 1999-07-21 | — | — | EP | disclosed |
| US-5475014-A | Monoamine oxidase inhibor; antidepressant | EISAI CO., LTD. (JP) | 1995-12-12 | — | — | US | disclosed |
| EP-0609441-A1 | OXAZOLIDONE DERIVATIVE | Eisai Co., Ltd. (JP) | 1994-08-10 | — | — | EP | disclosed |