Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 17/20 | 0.51 |
| ▸ | HTR4 | Q13639 | 15/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8305104 | 0.85 | HTR4 (0.44) | HTR4 | |
| Hydrochloric Acid SCHEMBL8368070 | 0.84 | HTR4 (0.43) | HTR4 | |
| SCHEMBL8309535 | 0.82 | DRD4 (0.44) | ACHEHTR4 | |
| SCHEMBL6961633 | 0.81 | HTR4 (0.47) | ACHEHTR4 | |
| SCHEMBL8304880 | 0.81 | HTR4 (0.44) | ACHEHTR4 | |
| Bromide SCHEMBL7744560 | 0.81 | HTR4 (0.46) | ACHEHTR4 | |
| Bromide SCHEMBL8366387 | 0.80 | HTR4 (0.43) | ACHEHTR4 | |
| SCHEMBL6961630 | 0.79 | HTR4 (0.36) | ACHEHTR4 | |
| SCHEMBL7804908 | 0.78 | HTR4 (0.48) | HTR4 | |
| Bromide SCHEMBL7744559 | 0.78 | HTR4 (0.36) | ACHEHTR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5929089-A | ANTISEROTONINE AGENT | SYNTHELABO (FR) | 1999-07-27 | — | — | US | disclosed |
| EP-0863897-B1 | 5-PHENYL-3-(PIPERIDIN-4-YL)-1,3,4-OXADIAZOL-2(3H)-ONE DERIVATIVES FOR USE AS 5-HT4- OR H3-RECEPTOR LIGANDS | SYNTHELABO (FR) | 1999-06-16 | — | — | EP | disclosed |