Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 13/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL7744560 | 0.99 | HTR4 (0.46) | HTR4MEN1ALDH1A1CYP2D6CYP2C9 | |
| SCHEMBL6967209 | 0.85 | DRD4 (0.37) | HTR4MEN1ALDH1A1CYP2D6CYP2C9 | |
| SCHEMBL8308214 | 0.84 | HTR4 (0.43) | HTR4MEN1ALDH1A1CYP2D6CYP2C9 | |
| SCHEMBL8305104 | 0.84 | HTR4 (0.44) | HTR4 | |
| Hydrochloric Acid SCHEMBL8364678 | 0.84 | HTR4 (0.43) | HTR4MEN1ALDH1A1CYP2D6CYP2C9 | |
| Hydrochloric Acid SCHEMBL8368070 | 0.83 | HTR4 (0.43) | HTR4 | |
| SCHEMBL6961630 | 0.83 | HTR4 (0.36) | HTR4ACHE | |
| Bromide SCHEMBL7744559 | 0.82 | HTR4 (0.36) | HTR4ACHE | |
| SCHEMBL8309549 | 0.81 | ACHE (0.51) | HTR4ACHE | |
| SCHEMBL8309535 | 0.81 | DRD4 (0.44) | HTR4CYP2D6CYP2C9ACHEKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0980368-B1 | 3-(PYRROLIDIN-3-YL)-1,3,4-OXADIAZOL-2(3H)-ONE DERIVATIVES AND THEIR USE AS 5-HT4 LIGANDS | SANOFI SYNTHELABO (FR) | 2003-10-22 | — | — | EP | disclosed |