Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | BCHE | P06276 | 2/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.36 |
| ▸ | LTK | P29376 | 1/20 | 0.36 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.36 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.36 |
| ▸ | CDK8 | P49336 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28778278 | 0.72 | ALDH1A1 (0.49) | ALDH1A1LMNAHPGDKDM4EMAPT | |
| Fluorene SCHEMBL29055454 | 0.68 | MAOA (0.48) | ALDH1A1LMNAHPGDKDM4EMAPT | |
| Fluorene SCHEMBL28275698 | 0.67 | MAOA (0.65) | ALDH1A1LMNAHPGDKDM4EMAPT | |
| Fluorene SCHEMBL27849096 | 0.67 | MAOA (0.65) | ALDH1A1LMNAHPGDKDM4EMAPT | |
| Fluorene SCHEMBL28894779 | 0.67 | ALDH1A1 (0.54) | ALDH1A1LMNAHPGDKDM4EMAPT | |
| Fluorene SCHEMBL28369012 | 0.67 | MAOA (0.52) | ALDH1A1LMNAHPGDKDM4EMAPT | |
| SCHEMBL2063312 | 0.67 | CES1 (0.42) | ALDH1A1LMNAHPGDKDM4EMAPT | |
| SCHEMBL9720856 | 0.67 | CES1 (0.42) | ALDH1A1LMNAHPGDKDM4EMAPT | |
| SCHEMBL4780109 | 0.66 | — | — | |
| Fluorene SCHEMBL28014522 | 0.65 | MAOA (0.62) | ALDH1A1LMNAHPGDKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5955615-A | COUPLERS | BAYER AKTIENGESELLSCHAFT (DE) | 1999-09-21 | — | — | US | disclosed |
| EP-0767220-B1 | Pyridonmethidazo dyes | BAYER AG (DE) | 1999-04-28 | — | — | EP | disclosed |
| US-5808015-A | RED FIBER REACTIVE, ACID DYES FOR CELLULOSE FIBERS, COTTON, WOOL, SILK, POLYAMIDES, POLYESTERS, POLYOLEFINS AND POLYACRYLONITRILE; COLORFASTNESS; BRIGHTNESS; TRIAZINE DYES | BAYER AKTIENGESELLSCHAFT (DE) | 1998-09-15 | — | — | US | disclosed |
| EP-0767220-A1 | Pyridonmethidazo dyes | BAYER AG (DE) | 1997-04-09 | — | — | EP | disclosed |