Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 7/20 | 0.37 |
| ▸ | CNR1 | P21554 | 6/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.34 |
| ▸ | ACVR1B | P36896 | 1/20 | 0.34 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.34 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17409984 | 0.84 | CNR2 (0.36) | KMT2ACNR2CNR1NPC1RAB9A | |
| SCHEMBL8306835 | 0.79 | HSD17B10 (0.39) | POLBKMT2AHPGDNTRK1HSD17B10 | |
| SCHEMBL15757732 | 0.76 | CES2 (0.47) | POLBAPEX1CNR2CNR1NPC1 | |
| SCHEMBL6421805 | 0.75 | HPGD (0.51) | POLBAPEX1CNR2CNR1NPC1 | |
| SCHEMBL8307823 | 0.74 | ALDH1A1 (0.37) | KMT2AATMHPGDSMN1; SMN2HSD17B10 | |
| SCHEMBL8391857 | 0.74 | ALDH1A1 (0.40) | POLBKMT2ANPC1RAB9AHPGD | |
| SCHEMBL8391653 | 0.73 | ABL1 (0.41) | KMT2ANPC1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL8309958 | 0.72 | HSD17B10 (0.39) | KMT2AHPGDSMN1; SMN2HSD17B10TSHR | |
| SCHEMBL8465283 | 0.72 | CES2 (0.49) | POLBKMT2ACNR2CNR1NPC1 | |
| SCHEMBL27413434 | 0.71 | POLB (0.55) | POLBKMT2ACNR2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0918056-A1 | Herbicides | RHONE-POULENC AGRICULTURE LTD. (GB) | 1999-05-26 | — | — | EP | disclosed |