Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | CTSV | O60911 | 1/20 | 0.34 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8311131 | 0.85 | EP300 (0.35) | DYRK1ACTSVTHRBLMNA | |
| SCHEMBL13219265 | 0.82 | CNR1 (0.32) | — | |
| SCHEMBL7270823 | 0.76 | GPR84 (0.37) | HTT | |
| SCHEMBL3032481 | 0.75 | — | — | |
| SCHEMBL13488505 | 0.75 | GPR84 (0.35) | — | |
| SCHEMBL9185542 | 0.75 | HSD17B10 (0.33) | — | |
| SCHEMBL361847 | 0.75 | KDM4E (0.50) | THRBLMNAHTT | |
| SCHEMBL30284405 | 0.75 | KDM4E (0.50) | THRBLMNAHTT | |
| SCHEMBL4253743 | 0.74 | APP (0.37) | LMNAHTT | |
| SCHEMBL12610512 | 0.74 | HSD17B1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0954761-A1 | PHOTOCHROMIC SUBSTITUTED NAPHTHOPYRAN COMPOUNDS | PPG Industries Ohio, Inc. (US) | 1999-11-10 | — | — | EP | disclosed |
| EP-0954761-A4 | — | — | 1999-11-10 | — | — | EP | disclosed |
| US-5744070-A | Photochromic substituted naphthopyran compounds | TRANSITIONS OPTICAL, INC. (US) | 1998-04-28 | — | — | US | disclosed |
| WO-1997022895-A1 | PHOTOCHROMIC SUBSTITUTED NAPHTHOPYRAN COMPOUNDS | PPG INDUSTRIES, INC. (US) | 1997-06-26 | — | — | WO | disclosed |