Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 3/20 | 0.44 |
| ▸ | GNAO1 | P09471 | 3/20 | 0.44 |
| ▸ | GNAI1 | P63096 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12641 | 0.82 | GNAI3 (0.45) | GNAI3GNAO1GNAI1POLBHPGD | |
| SCHEMBL12016032 | 0.82 | GNAI3 (0.45) | GNAI3GNAO1GNAI1POLBHPGD | |
| SCHEMBL772816 | 0.80 | GNAI3 (0.44) | GNAI3GNAO1GNAI1POLBHPGD | |
| SCHEMBL14814157 | 0.80 | GNAI3 (0.44) | GNAI3GNAO1GNAI1POLBHPGD | |
| SCHEMBL4518519 | 0.80 | GNAI3 (0.51) | GNAI3GNAO1GNAI1POLBHPGD | |
| SCHEMBL10274497 | 0.78 | GNAI3 (0.58) | GNAI3GNAO1GNAI1HSD11B1ALDH1A1 | |
| SCHEMBL18997472 | 0.78 | GNAI3 (0.43) | GNAI3GNAO1GNAI1POLBHPGD | |
| SCHEMBL24550501 | 0.77 | ALDH1A1 (0.61) | GNAI3GNAO1GNAI1POLBHSD11B1 | |
| SCHEMBL18513691 | 0.77 | FAAH (0.48) | GNAI3GNAO1GNAI1MEN1KMT2A | |
| SCHEMBL14330457 | 0.77 | EPHX1 (0.46) | GNAI3GNAO1GNAI1POLBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004056823-A1 | PYRAZOLO[3,4-b]PYRIDINE COMPOUNDS, AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2004-07-08 | — | — | WO | disclosed |