Sugi Predict

Sugi Predict / Compounds / SCHEMBL8310563

SCHEMBL8310563

SCHEMBL8310563

OC(OCC1CCCCO1)C1CCC1

nearest known ligand 0.40

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 2/20 0.40
▸ MEN1 O00255 1/20 0.40
▸ LMNA P02545 1/20 0.39
▸ POLB P06746 1/20 0.39
▸ NPC1 O15118 1/20 0.37
▸ RAB9A P51151 1/20 0.37
▸ SMN1; SMN2 Q16637 1/20 0.37
▸ ALDH1A1 P00352 1/20 0.37
▸ MGLL Q99685 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3389065 0.79 LMNA (0.41) KMT2AMEN1LMNAPOLBNPC1
SCHEMBL12448236 0.78 MEN1 (0.40) KMT2AMEN1LMNAPOLBALDH1A1
SCHEMBL12595150 0.75 LMNA (0.41) KMT2AMEN1LMNAPOLBNPC1
SCHEMBL3389771 0.73 LMNA (0.46) KMT2AMEN1LMNAPOLBSMN1; SMN2
SCHEMBL23977846 0.72 LMNA (0.44) KMT2AMEN1LMNAPOLBNPC1
SCHEMBL26832966 0.72 LMNA (0.44) KMT2AMEN1LMNAPOLBNPC1
SCHEMBL2700038 0.72 LMNA (0.44) KMT2AMEN1LMNAPOLBNPC1
SCHEMBL12595149 0.71 LMNA (0.38) KMT2AMEN1LMNAPOLBNPC1
SCHEMBL6975491 0.71 TSHR (0.46) LMNAPOLBNPC1RAB9ASMN1; SMN2
SCHEMBL20925407 0.70 MGLL (0.46) MGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0924209-A1 Hypoglycemic imidazoline compounds ELI LILLY AND COMPANY (US) 1999-06-23 — — EP disclosed