Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.49 |
| ▸ | PPARA | Q07869 | 2/20 | 0.49 |
| ▸ | ACE | P12821 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.44 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8310591 | 1.00 | PPARG (0.49) | PPARGPPARAACEPTPN1NR4A1 | |
| SCHEMBL8307913 | 0.85 | TSHR (0.54) | ACETSHRSMN1; SMN2CTSLPAM | |
| SCHEMBL8307911 | 0.85 | TSHR (0.54) | ACETSHRSMN1; SMN2CTSLPAM | |
| SCHEMBL16641857 | 0.83 | ALDH1A1 (0.46) | PPARGPPARAACEGSK3BLMNA | |
| SCHEMBL16641859 | 0.83 | ALDH1A1 (0.46) | PPARGPPARAACEGSK3BLMNA | |
| SCHEMBL8310917 | 0.83 | GPR139 (0.51) | PPARGPPARASMN1; SMN2PAM | |
| SCHEMBL8310911 | 0.83 | GPR139 (0.51) | PPARGPPARASMN1; SMN2PAM | |
| SCHEMBL1404293 | 0.82 | ACE (0.40) | PPARGPPARAACEL3MBTL1FPR2 | |
| SCHEMBL374424 | 0.82 | ACE (0.40) | PPARGPPARAACEL3MBTL1FPR2 | |
| SCHEMBL8308373 | 0.80 | PPARG (0.48) | PPARGPPARAACEHDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0903346-A1 | SYDNONE IMINE DERIVATIVES | Chugai Seiyaku Kabushiki Kaisha (JP) | 1999-03-24 | — | — | EP | disclosed |