Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | ACE | P12821 | 1/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 5/20 | 0.42 |
| ▸ | PAM | P19021 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | THPO | P40225 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.39 |
| ▸ | PRNP | P04156 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8307913 | 1.00 | TSHR (0.54) | TSHRKMT2AACEFOLH1PAM | |
| SCHEMBL16641857 | 0.87 | ALDH1A1 (0.46) | TSHRKMT2AACEPAMKDM4E | |
| SCHEMBL16641859 | 0.87 | ALDH1A1 (0.46) | TSHRKMT2AACEPAMKDM4E | |
| SCHEMBL8310917 | 0.87 | GPR139 (0.51) | KMT2APAMKDM4EMAPTTHRB | |
| SCHEMBL8310911 | 0.87 | GPR139 (0.51) | KMT2APAMKDM4EMAPTTHRB | |
| SCHEMBL8310589 | 0.85 | PPARG (0.49) | TSHRACEPAMSMN1; SMN2CTSL | |
| SCHEMBL8310591 | 0.85 | PPARG (0.49) | TSHRACEPAMSMN1; SMN2CTSL | |
| SCHEMBL8308373 | 0.83 | PPARG (0.48) | KMT2AACEMAPTCA2 | |
| SCHEMBL8308366 | 0.83 | PPARG (0.48) | KMT2AACEMAPTCA2 | |
| SCHEMBL10363718 | 0.82 | PAM (0.52) | KMT2APAMKDM4EMAPTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0903346-A1 | SYDNONE IMINE DERIVATIVES | Chugai Seiyaku Kabushiki Kaisha (JP) | 1999-03-24 | — | — | EP | disclosed |