Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | JAK1 | P23458 | 1/20 | 0.40 |
| ▸ | CCR1 | P32246 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TACR1 | P25103 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 2/20 | 0.38 |
| ▸ | YAP1 | P46937 | 2/20 | 0.38 |
| ▸ | NR1D1 | P20393 | 2/20 | 0.38 |
| ▸ | VEGFA | P15692 | 1/20 | 0.37 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8312282 | 0.93 | YAP1 (0.41) | OPRD1OPRK1JAK2JAK1CCR1 | |
| SCHEMBL6094817 | 0.93 | YAP1 (0.41) | OPRD1OPRK1JAK2JAK1CCR1 | |
| SCHEMBL6094822 | 0.93 | YAP1 (0.41) | OPRD1OPRK1JAK2JAK1CCR1 | |
| SCHEMBL8306441 | 0.92 | CCR5 (0.40) | OPRD1OPRK1JAK2JAK1CCR1 | |
| SCHEMBL6094255 | 0.92 | CCR5 (0.40) | OPRD1OPRK1JAK2JAK1CCR1 | |
| SCHEMBL6273383 | 0.92 | CCR5 (0.40) | OPRD1OPRK1JAK2JAK1CCR1 | |
| SCHEMBL6094257 | 0.92 | CCR5 (0.40) | OPRD1OPRK1JAK2JAK1CCR1 | |
| SCHEMBL6273386 | 0.92 | CCR5 (0.40) | OPRD1OPRK1JAK2JAK1CCR1 | |
| SCHEMBL14028090 | 0.82 | TACR1 (0.46) | OPRD1OPRK1JAK2JAK1TACR1 | |
| SCHEMBL6094818 | 0.81 | CCR1 (0.41) | CCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004080460-A1 | SUBSTITUTED PIPERIDINES AS NOVEL MDM2-p53 INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2004-09-23 | — | — | WO | disclosed |