Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | MIF | P14174 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | F12 | P00748 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9121263 | 0.68 | MAOA (0.49) | ALDH1A1MAPTKDM4EGAAHPGD | |
| SCHEMBL11456120 | 0.66 | ESR1 (0.45) | ALDH1A1MAPTKDM4EHPGDLMNA | |
| SCHEMBL8311003 | 0.63 | FLT3 (0.65) | ALDH1A1MAPTKDM4EGAAHPGD | |
| SCHEMBL12474263 | 0.62 | LCK (0.44) | ALDH1A1MAPTHPGDGLANPSR1 | |
| SCHEMBL1533447 | 0.61 | CYP1A2 (0.57) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL6608929 | 0.61 | MCL1 (0.49) | ALDH1A1KDM4EHPGDMEN1KMT2A | |
| SCHEMBL7633234 | 0.61 | PIM1 (0.45) | ALDH1A1MAPTKDM4EHPGDMEN1 | |
| SCHEMBL1692369 | 0.60 | CYP1A2 (0.55) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL29899643 | 0.60 | CYP1A2 (0.55) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL28065505 | 0.58 | CA12 (0.50) | ALDH1A1KDM4EGAAHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0528337-B1 | New thiazolylbenzofuran derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO (JP) | 1999-10-20 | — | — | EP | disclosed |
| US-5296495-A | Antiallergens, antiinflammatory | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-03-22 | — | — | US | disclosed |
| EP-0528337-A1 | New thiazolylbenzofuran derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-02-24 | — | — | EP | disclosed |