Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8311327 | 1.00 | NLRP3 (0.32) | NLRP3LMNAGAA | |
| SCHEMBL8313823 | 0.86 | LMNA (0.32) | LMNAGAA | |
| SCHEMBL8313821 | 0.86 | LMNA (0.32) | LMNAGAA | |
| SCHEMBL8315510 | 0.81 | LMNA (0.31) | LMNAGAA | |
| SCHEMBL8315506 | 0.81 | LMNA (0.31) | LMNAGAA | |
| SCHEMBL8316411 | 0.80 | LMNA (0.30) | LMNAGAA | |
| SCHEMBL8312545 | 0.78 | LMNA (0.31) | LMNAGAA | |
| SCHEMBL8311675 | 0.78 | LMNA (0.31) | LMNAGAA | |
| SCHEMBL8312546 | 0.78 | LMNA (0.31) | LMNAGAA | |
| SCHEMBL8314611 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0562439-B1 | Triazolopyridazines as antioasthmatics | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1999-06-09 | — | — | EP | disclosed |
| EP-0548923-B1 | Antiallergic, antiinflammatory and anti-PAF pyridazine compounds | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1998-07-08 | — | — | EP | disclosed |
| US-5482939-A | ANTI-PLATELET ACTIVATING FACTOR ACTIVITIES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-01-09 | — | — | US | disclosed |
| US-5389633-A | ANTIASTHMATIC AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-02-14 | — | — | US | disclosed |
| US-5369104-A | Antiasthmatic agents | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-11-29 | — | — | US | disclosed |
| EP-0562439-A1 | Triazolopyridazines as antioasthmatics | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-09-29 | — | — | EP | disclosed |
| EP-0548923-A2 | Antiallergic, antiinflammatory and anti-PAF pyridazine compounds | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-06-30 | — | — | EP | disclosed |