Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8313821 | 1.00 | LMNA (0.32) | LMNAGAA | |
| SCHEMBL8311331 | 0.86 | NLRP3 (0.32) | LMNAGAA | |
| SCHEMBL8311327 | 0.86 | NLRP3 (0.32) | LMNAGAA | |
| SCHEMBL8312546 | 0.79 | LMNA (0.31) | LMNAGAA | |
| SCHEMBL8315510 | 0.79 | LMNA (0.31) | LMNAGAA | |
| SCHEMBL8315506 | 0.79 | LMNA (0.31) | LMNAGAA | |
| SCHEMBL8312545 | 0.79 | LMNA (0.31) | LMNAGAA | |
| SCHEMBL8311675 | 0.79 | LMNA (0.31) | LMNAGAA | |
| SCHEMBL8316411 | 0.78 | LMNA (0.30) | LMNAGAA | |
| SCHEMBL8314607 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0562439-B1 | Triazolopyridazines as antioasthmatics | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1999-06-09 | — | — | EP | disclosed |
| US-5482939-A | ANTI-PLATELET ACTIVATING FACTOR ACTIVITIES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-01-09 | — | — | US | disclosed |
| US-5389633-A | ANTIASTHMATIC AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-02-14 | — | — | US | disclosed |
| EP-0562439-A1 | Triazolopyridazines as antioasthmatics | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-09-29 | — | — | EP | disclosed |