Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.38 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7313877 | 0.85 | PKM (0.46) | PKMMAPTHDAC3HDAC4HDAC1 | |
| SCHEMBL3191250 | 0.85 | PKM (0.46) | PKMMAPTHDAC3HDAC4HDAC1 | |
| SCHEMBL8313331 | 0.79 | PIN1 (0.39) | PKMMAPTHDAC3HDAC4HDAC1 | |
| SCHEMBL6671866 | 0.79 | PKM (0.44) | PKMMAPTHDAC3HDAC4HDAC1 | |
| Hydrochloric Acid SCHEMBL8312738 | 0.78 | PIN1 (0.38) | PKMMAPTHDAC3HDAC4HDAC1 | |
| SCHEMBL74015 | 0.76 | MAPT (0.48) | PKMMAPTHDAC3HDAC4HDAC1 | |
| SCHEMBL9764850 | 0.75 | ALOX5 (0.51) | PKMMAPTHDAC3HDAC4HDAC1 | |
| SCHEMBL6844569 | 0.75 | CYP2A6 (0.49) | PKMMAPTHDAC3HDAC4HDAC1 | |
| SCHEMBL4232293 | 0.74 | PKM (0.46) | PKMMAPTHDAC3HDAC4HDAC1 | |
| SCHEMBL10559844 | 0.74 | ALOX5 (0.50) | PKMMAPTHDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0635508-B1 | TETRAHYDROPYRIDINE DERIVATIVE HAVING SUBSTITUENTS ON THREE RINGS | ASAHI CHEMICAL IND (JP) | 1999-10-06 | — | — | EP | disclosed |
| US-5621103-A | 3-(SUBSTITUTED METHYLAMINOCARBONYL)-1,2,3,4-TETRAHYDRO-(1)BENZOTHIENO(2,3-C) PYRIDINES; ANXIOLYTIC AGENTS; LEARNING ENHANCEMENT | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1997-04-15 | — | — | US | disclosed |
| EP-0635508-A1 | TETRAHYDROPYRIDINE DERIVATIVE HAVING SUBSTITUENTS ON THREE RINGS | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1995-01-25 | — | — | EP | disclosed |
| EP-0386258-A1 | TETRAHYDROPYRIDINE DERIVATIVES | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1990-09-12 | — | — | EP | disclosed |