Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 3/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | GABRP | O00591 | 1/20 | 0.37 |
| ▸ | GABRD | O14764 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.37 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.37 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8312738 | 0.99 | PIN1 (0.38) | PIN1PKMCYP2A6MMP8SMN1; SMN2 | |
| SCHEMBL9282618 | 0.83 | POLB (0.40) | PIN1PKMCYP2A6SMN1; SMN2TP53 | |
| SCHEMBL8311679 | 0.79 | PKM (0.45) | PKMCYP2A6SMN1; SMN2TP53RXFP1 | |
| SCHEMBL4232293 | 0.74 | PKM (0.46) | PKMCYP2A6SMN1; SMN2TP53RXFP1 | |
| SCHEMBL1455978 | 0.72 | PIN1 (0.51) | PIN1MMP8SMN1; SMN2MAPTKMT2A | |
| SCHEMBL27752471 | 0.72 | PIN1 (0.51) | PIN1MMP8SMN1; SMN2MAPTKMT2A | |
| SCHEMBL27731921 | 0.72 | PIN1 (0.51) | PIN1MMP8SMN1; SMN2MAPTKMT2A | |
| SCHEMBL9494725 | 0.72 | TSHR (0.58) | SMN1; SMN2TP53MAPTKMT2AALDH1A1 | |
| SCHEMBL10559326 | 0.71 | ALOX5 (0.39) | PKMCYP2A6SMN1; SMN2TP53RXFP1 | |
| SCHEMBL12262385 | 0.71 | CYP2A6 (0.46) | PKMCYP2A6SMN1; SMN2TP53RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0635508-B1 | TETRAHYDROPYRIDINE DERIVATIVE HAVING SUBSTITUENTS ON THREE RINGS | ASAHI CHEMICAL IND (JP) | 1999-10-06 | — | — | EP | disclosed |
| US-5621103-A | 3-(SUBSTITUTED METHYLAMINOCARBONYL)-1,2,3,4-TETRAHYDRO-(1)BENZOTHIENO(2,3-C) PYRIDINES; ANXIOLYTIC AGENTS; LEARNING ENHANCEMENT | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1997-04-15 | — | — | US | disclosed |
| EP-0635508-A1 | TETRAHYDROPYRIDINE DERIVATIVE HAVING SUBSTITUENTS ON THREE RINGS | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1995-01-25 | — | — | EP | disclosed |
| EP-0386258-A1 | TETRAHYDROPYRIDINE DERIVATIVES | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1990-09-12 | — | — | EP | disclosed |