Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 6/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TACR1 | P25103 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4836403 | 0.88 | SLC6A4 (0.43) | SLC6A4SLC6A2SLC6A3HTR2CGAA | |
| SCHEMBL5374397 | 0.88 | OPRD1 (0.39) | SLC6A4SLC6A2SLC6A3HTR2COPRD1 | |
| SCHEMBL7306627 | 0.86 | ALDH1A1 (0.45) | SLC6A4SLC6A2SLC6A3HTR2CGAA | |
| SCHEMBL6019029 | 0.85 | CTSL (0.42) | SLC6A4SLC6A2SLC6A3HTR2CGAA | |
| SCHEMBL23780011 | 0.85 | CTSL (0.42) | SLC6A4SLC6A2SLC6A3HTR2CGAA | |
| SCHEMBL409358 | 0.84 | TDP1 (0.41) | — | |
| SCHEMBL1672995 | 0.84 | TDP1 (0.41) | — | |
| SCHEMBL6605312 | 0.82 | HTR2C (0.47) | SLC6A4SLC6A2SLC6A3HTR2CGAA | |
| SCHEMBL12361199 | 0.81 | OPRD1 (0.37) | SLC6A4SLC6A2SLC6A3OPRD1KMT2A | |
| SCHEMBL12156572 | 0.80 | CTSL (0.42) | SLC6A4SLC6A2SLC6A3HTR2CGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5958373-A | Polychelants as contrast enhancing agents | NYCOMED SALUTAR INC. (US) | 1999-09-28 | — | — | US | disclosed |
| EP-0717737-B1 | CHELANTS AS CONTRAST ENHANCING AGENTS | NYCOMED SALUTAR INC (US) | 1999-04-07 | — | — | EP | disclosed |
| EP-0717737-A1 | CHELANTS AS CONTRAST ENHANCING AGENTS | NYCOMED SALUTAR, INC. (US) | 1996-06-26 | — | — | EP | disclosed |
| WO-1995007270-A1 | CHELANTS AS CONTRAST ENHANCING AGENTS | NYCOMED SALUTAR, INC. (US) | 1995-03-16 | — | — | WO | disclosed |