Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 6/20 | 0.47 |
| ▸ | DRD2 | P14416 | 6/20 | 0.47 |
| ▸ | HTR7 | P34969 | 6/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | IDO1 | P14902 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6811167 | 0.96 | CHRM4 (0.50) | CHRM4DRD2HTR7BRD4ATAD2 | |
| SCHEMBL8307649 | 0.90 | CHRM4 (0.49) | CHRM4DRD2HTR7BRD4ATAD2 | |
| SCHEMBL8312961 | 0.79 | HSP90AA1 (0.46) | CHRM4DRD2HTR7 | |
| SCHEMBL4455923 | 0.76 | IDO1 (0.58) | CHRM4DRD2HTR7IDO1 | |
| SCHEMBL30290988 | 0.76 | IDO1 (0.58) | CHRM4DRD2HTR7IDO1 | |
| SCHEMBL6987694 | 0.75 | MTNR1A (0.52) | CHRM4DRD2HTR7 | |
| SCHEMBL8308233 | 0.74 | CHRM4 (0.47) | CHRM4DRD2HTR7 | |
| SCHEMBL10286869 | 0.74 | CHRM4 (0.35) | CHRM4DRD2HTR7BRD4ATAD2 | |
| SCHEMBL6190630 | 0.73 | BRD4 (0.40) | CHRM4DRD2HTR7BRD4ATAD2 | |
| SCHEMBL25904940 | 0.73 | DRD2 (0.50) | CHRM4DRD2HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004087124-A1 | COMPOUNDS HAVING SEROTONIN 5-HT17 RECEPTOR ANTAGONIST ACTIVITY AND MUSCARINIC M4 RECEPTOR AGONIST ACTIVITY AND THEIR USE IN THE TREATMENT OF PSYCHOTIC DISORDERS | MITSUBISHI PHARMA CORPORATION (JP) | 2004-10-14 | — | — | WO | disclosed |