Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 5/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 4/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.33 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.32 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.32 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.32 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8316452 | 0.82 | OPRD1 (0.35) | OPRD1OPRK1GAAKCNH2CTDSP1 | |
| SCHEMBL8313482 | 0.79 | MEN1 (0.30) | OPRD1CYP2D6OPRK1KCNH2MEN1 | |
| SCHEMBL8313997 | 0.78 | MAPT (0.49) | PDK2CTDSP1GLAALDH1A1MAPT | |
| SCHEMBL8316122 | 0.78 | EPHX2 (0.30) | — | |
| SCHEMBL8311296 | 0.78 | AKR1B1 (0.37) | GAAALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL8317179 | 0.69 | BRD4 (0.36) | GAAPDK2ALDH1A1FGFR1FGFR2 | |
| SCHEMBL26349874 | 0.65 | PLK1 (0.36) | OPRD1CYP2D6OPRK1GAAPDK2 | |
| SCHEMBL7094132 | 0.64 | CFTR (0.41) | ALDH1A1MAPTKMT2A | |
| SCHEMBL6270480 | 0.62 | PTGS1 (0.38) | ALDH1A1 | |
| SCHEMBL6557433 | 0.61 | ALDH1A1 (0.33) | ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0632033-B1 | NOVEL BENZOPYRAN DERIVATIVE | CHUGAI PHARMACEUTICAL CO LTD (JP) | 1999-04-07 | — | — | EP | disclosed |
| US-5646308-A | POTASSIUM CHANNEL ACTIVATORS USED AS ANTIASTHMATICS, ANTIEPILEPTICS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1997-07-08 | — | — | US | disclosed |
| EP-0632033-A1 | NOVEL BENZOPYRAN DERIVATIVE | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1995-01-04 | — | — | EP | disclosed |