Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | GLA | P06280 | 2/20 | 0.49 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | BLM | P54132 | 2/20 | 0.40 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | APAF1 | O14727 | 2/20 | 0.39 |
| ▸ | TDP2 | O95551 | 1/20 | 0.39 |
| ▸ | NSD2 | O96028 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8313694 | 0.83 | ALPG (0.41) | MAPTALDH1A1KMT2ATSHRKDM4E | |
| SCHEMBL6269237 | 0.83 | LMNA (0.40) | MAPTALDH1A1GLACTDSP1MEN1 | |
| SCHEMBL6269700 | 0.83 | ALDH1A1 (0.36) | MAPTALDH1A1GLACTDSP1MEN1 | |
| Hydrochloric Acid SCHEMBL8316265 | 0.82 | LMNA (0.40) | MAPTALDH1A1GLACTDSP1MEN1 | |
| SCHEMBL8316452 | 0.80 | OPRD1 (0.35) | MAPTALDH1A1GLACTDSP1MEN1 | |
| SCHEMBL6268793 | 0.79 | ALDH1A1 (0.33) | MAPTALDH1A1GLACTDSP1MEN1 | |
| SCHEMBL8313588 | 0.78 | OPRD1 (0.40) | MAPTALDH1A1GLACTDSP1MEN1 | |
| SCHEMBL6269249 | 0.77 | MLYCD (0.32) | MAPTALDH1A1GLACTDSP1MEN1 | |
| SCHEMBL8316142 | 0.77 | KMT2A (0.35) | MAPTALDH1A1GLACTDSP1MEN1 | |
| SCHEMBL7487263 | 0.71 | ALDH1A1 (0.47) | MAPTALDH1A1GLACTDSP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0632033-B1 | NOVEL BENZOPYRAN DERIVATIVE | CHUGAI PHARMACEUTICAL CO LTD (JP) | 1999-04-07 | — | — | EP | disclosed |
| US-5646308-A | POTASSIUM CHANNEL ACTIVATORS USED AS ANTIASTHMATICS, ANTIEPILEPTICS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1997-07-08 | — | — | US | disclosed |
| EP-0632033-A1 | NOVEL BENZOPYRAN DERIVATIVE | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1995-01-04 | — | — | EP | disclosed |