Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 4/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.32 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.32 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.32 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8313588 | 0.69 | OPRD1 (0.40) | GAAMEN1KMT2AALDH1A1FGFR1 | |
| SCHEMBL26349874 | 0.65 | PLK1 (0.36) | GAAALDH1A1KDM4EFGFR1FGFR2 | |
| SCHEMBL19026286 | 0.63 | KDM4E (0.38) | MEN1KMT2AALDH1A1KDM4EHSD17B10 | |
| SCHEMBL11107356 | 0.60 | LMNA (0.47) | MEN1KMT2AALDH1A1KDM4EHSD17B10 | |
| SCHEMBL11745008 | 0.60 | GAA (0.41) | GAAALDH1A1KDM4EFGFR1FGFR2 | |
| SCHEMBL4325382 | 0.59 | RET (0.39) | MEN1KMT2AALDH1A1KDM4EHSD17B10 | |
| SCHEMBL11410287 | 0.58 | GAA (0.63) | BRD4GAAMEN1KMT2AALDH1A1 | |
| SCHEMBL26337388 | 0.57 | ALDH1A1 (0.41) | BRD4GAAALDH1A1KDM4EHSD17B10 | |
| SCHEMBL28031186 | 0.57 | MAPT (0.44) | GAAALDH1A1KDM4EHSD17B10FGFR1 | |
| SCHEMBL18175172 | 0.57 | ALDH1A1 (0.39) | MEN1KMT2AALDH1A1KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0632033-B1 | NOVEL BENZOPYRAN DERIVATIVE | CHUGAI PHARMACEUTICAL CO LTD (JP) | 1999-04-07 | — | — | EP | disclosed |