Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 10/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | BRD3 | Q15059 | 3/20 | 0.40 |
| ▸ | CREBBP | Q92793 | 3/20 | 0.40 |
| ▸ | BRD7 | Q9NPI1 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | BAZ2B | Q9UIF8 | 2/20 | 0.37 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.37 |
| ▸ | BPTF | Q12830 | 1/20 | 0.37 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14288686 | 0.78 | ACLY (0.51) | BRD4ALDH1A1KDM4ERXFP1MEN1 | |
| SCHEMBL3842730 | 0.65 | LCK (0.54) | ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL8067195 | 0.61 | KDM4E (0.71) | BRD4ALDH1A1KDM4EMEN1KMT2A | |
| Sulfuric Acid SCHEMBL28870881 | 0.61 | KMT2A (0.59) | ALDH1A1KDM4EL3MBTL1MEN1KMT2A | |
| SCHEMBL30416850 | 0.61 | MEN1 (0.57) | KDM4ERXFP1L3MBTL1MEN1KMT2A | |
| SCHEMBL20610091 | 0.61 | MEN1 (0.57) | KDM4ERXFP1L3MBTL1MEN1KMT2A | |
| SCHEMBL3040658 | 0.60 | KDR (0.52) | ALDH1A1KDM4EL3MBTL1MEN1KMT2A | |
| SCHEMBL10242038 | 0.60 | BRD4 (1.00) | BRD4ALDH1A1HPGDBRD3CREBBP | |
| SCHEMBL25979896 | 0.59 | ERN1 (0.44) | ALDH1A1HPGDL3MBTL1POLB | |
| Iodobenzene SCHEMBL9311593 | 0.59 | TSHR (0.50) | ALDH1A1KDM4EHPGDRXFP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004073634-A2 | PHENYLENEDIAMINE UROTENSIN-II RECEPTOR ANTAGONISTS AND CCR-9 ANTAGONISTS | ENCYSIVE PHARMACEUTICALS INC. (US) | 2004-09-02 | — | — | WO | disclosed |